Irie Genetics is a cannabis breeder of renown, founded by renowned breeder Rasta Jeff. Its mission is to develop vibrant, flavorful and potent strains that are able to thrive in a variety of growing conditions. Irie Genetics cultivates a wide range of strains including Lemon Jeffery, Arise and Orange Gasm.

This irie genetics builds upon previous research indicating that expression level stability contributes to evolutionary conservation. We performed a cross experiment in medaka to determine whether stability in the F0 generation correlates with genetic diversity in the hybrid F3 descendants on a gene-by-gene basis. We found that genes with lower expression level variability in the F0 population exhibit less diversity in the hybrid F3 populations (Spearman p0.01). Developmental stages with greater developmental stability also exhibit reduced genetic diversity in the F3 descendants.

Satisfy Your Sweet Tooth: Diving into the Cake Pop Strain

eimplantation germ cells (hPGCs) isolated from medically or surgically terminated embryos at Addenbrooke’s Hospital (Cambridge, UK), we performed a genome-wide analysis of CpG methylation dynamics during chromatin remodeling and demethylation in the germline. We observed a comprehensive wave of global DNA demethylation in Wk7-9 hPGCs, with the majority of CpG loci being unmethylated and accessible to transcription. Nevertheless, some single and repeat CpG loci remained partially methylated in the germline and could therefore be candidates for transgenerational epigenetic inheritance.

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